Introduction
A jacketed glass reactor is a laboratory reactor with a double-walled glass vessel, in which the space between the walls is used for the circulation of the heating or the cooling fluid, and it is used in the chemistry, the pharmaceutical, the chemical engineering, and the research laboratories for the reactions under the controlled temperature. The jacketed glass reactor consists of a glass vessel with an inner layer and an outer jacket, a circulation system for the heating or the cooling fluid, such as the water or the oil, a stirring system, a reflux condenser, and the inlets and the outlets for the addition and the sampling, and it provides the controlled temperature of the reaction by the circulation of the fluid through the jacket, with a high uniformity and a precise control, with features such as the adjustable stirring speed, the temperature control, and the vacuum connection; the jacketed glass reactor is used for the chemical synthesis, for the reactions at the controlled temperature, for the exothermic and the endothermic reactions, for the distillation and the reflux, for the crystallization, for the reactions under the vacuum, and for many other applications, and it is available in various capacities, from the small laboratory models to the larger models, with the various stirring and the heating configurations; the jacketed glass reactor is an essential instrument for the temperature-controlled reactions in the laboratory. Jacketed glass reactors are used in the chemistry laboratories, in the pharmaceutical industry, in the chemical engineering, in the research institutions, and for many other applications. With their temperature control, jacketed glass reactors are essential for the controlled reactions.
Jacketed Glass Reactor LJGR-T2028
Jacketed Glass Reactor has a 0.5 L capacity and features a compact design. It is built to withstand high temperatures offering low thermal expansion, providing strong corrosion resistanc...
Jacketed Glass Reactor LJGR-T2027
Jacketed Glass Reactor with a 100L glass vessel supports batch operations involving large-volume reactions. The stirring system enables wide speed adjustment so users can match the agita...
Jacketed Glass Reactor LJGR-T2026
Jacketed Glass Reactor features a 100L glass vessel volume, enabling large-batch reactions for extended experimental runs. It includes a solid charging port that allows safe input of mat...
Jacketed Glass Reactor LJGR-T2025
Jacketed Glass Reactor features a glass vessel volume of 100L, improving surface‑to‑volume ratio and uniform temperature control for safer thermal management. It is equipped with advan...
Jacketed Glass Reactor LJGR-T2024
Jacketed Glass Reactor offers a jacketed volume of 18L, providing uniform and efficient heat or cooling transfer around the reaction vessel. The reactor features a zero dead space bottom...
Jacketed Glass Reactor LJGR-T2023
Jacket Glass Reactor features a vacuum degree of 0.098 MPa for conducting sensitive distillation or crystallization under controlled negative pressure. The reactor has a double-layer jac...
Jacketed Glass Reactor LJGR-T2022
Jacketed Glass Reactor features a temperature range of -60 to 200°C for accurate thermal control from moderate cooling to elevated heating. The unit provides a six-neck lid, enabling si...
Jacketed Glass Reactor LJGR-T2021
Jacketed Glass Reactor offers a jacketed volume of 6L, providing uniform and efficient heat or cooling transfer around the reaction vessel. It is equipped with advanced high-quality boro...
Jacketed Glass Reactor LJGR-T2020
Jacketed Glass Reactor features a glass vessel volume of 5L, improving surface-to-volume ratio and uniform temperature control for safer thermal management. The reactor provides -coated ...
Jacketed Glass Reactor LJGR-T2019
Jacketed Glass Reactor features a 100 processes in labs and industrial settings. This laboratory glass reactor is designed to meet the rigorous requirements of modern laboratory operatio...
Jacketed Glass Reactor LJGR-T2018
Jacketed Glass Reactor features a 100 chemical processes with stable performance. The reactor includes a high clearance drain port that allows direct discharge of processed materials wit...
Jacketed Glass Reactor LJGR-T2017
Jacketed Glass Reactor features a 50 jacket interface. It includes a high clearance drain port for direct discharge without moving the receiving vessel. Our reactor is used in synthesis,...
Jacketed Glass Reactor LJGR-T2016
Jacketed Glass Reactor features a 50 L cylindrical vessel that supports synthesis, distillation, and concentration in advanced lab environments. The reinforced glass flange ensures tight...
Jacketed Glass Reactor LJGR-T2015
Jacketed Glass Reactor features a 30 synthesis and thermal processing across research workflows. The dual-layer jacket maintains consistent internal temperatures by circulating heating o...
Jacketed Glass Reactor LJGR-T2014
Jacketed Glass Reactor features a 30 reactions while maintaining structural stability. Its top opening allows efficient material addition without interrupting ongoing processes. The low ...
Jacketed Glass Reactor LJGR-T2013
Jacketed Glass Reactor features a 20 synthesis and temperature-sensitive operations in lab environments. The elevated drain port enables easy discharge while reducing material residue. I...
Jacketed Glass Reactor LJGR-T2012
Jacketed Glass Reactor features a 20 lid supports easy integration of accessories like feeding ports and condensers. Our Jacketed Glass Reactor is used for synthesis, distillation, and e...
Jacketed Glass Reactor LJGR-T2011
Jacketed Glass Reactor features a 10 lid supports flexible placement of condensers, funnels, sensors, or gas inlets during complex procedures. The reinforced jacket and glass flange redu...
Jacketed Glass Reactor LJGR-T2010
Jacketed Glass Reactor includes a 10 reactions requiring controlled thermal conditions. The solid charging port allows bulk material addition without disrupting the process. Its optional...
Jacketed Glass Reactor LJGR-T2050
Jacketed Glass Reactor features a 5 lid allows easy attachment of instruments for uninterrupted reaction monitoring. Its jacket design enables uniform temperature distribution during exp...
Jacketed Glass Reactor LJGR-T2049
Jacketed Glass Reactor features a 5 lid supports simultaneous feeding, sampling, and sensor integration without halting the process. Our Jacketed Glass Reactor is used in synthesis, dist...
Jacketed Glass Reactor LJGR-T2048
Jacketed Glass Reactor includes a 3 lid design that allows quick access during setup or cleaning. The stable support frame helps reduce vibrations during prolonged experimental runs. Our...
Jacketed Glass Reactor LJGR-T2047
Jacketed Glass Reactor features a 2 synthesis and controlled chemical processing. The multi-port lid arrangement accommodates diverse experimental setups without limiting operational acc...
Jacketed Glass Reactor LJGR-T2046
It is the supplier of Jacketed Glass Reactor with a 100 mm drain port clearance that supports safe discharge and convenient sample collection. Its 25 mm jacket interface ensures steady l...
Jacketed Glass Reactor LJGR-T2045
Jacketed Glass Reactor includes a 100 L cylindrical vessel designed for efficient thermal regulation through its dual-layer jacket. The vacuum-capable build supports pressure-controlled...
Jacketed Glass Reactor LJGR-T2044
Jacketed Glass Reactor features a 50 jacket design. It includes a dropping funnel for controlled reagent addition, reducing risks during sensitive processes. The wide temperature range s...
Jacketed Glass Reactor LJGR-T2043
Jacketed Glass Reactor features a 20 applications. The handwheel allows the vessel to tilt left, making pouring and cleaning more convenient. The overhead setup allows vertical adjustmen...
Jacketed Glass Reactor LJGR-T2042
Jacketed Glass Reactor includes a 10 L cylindrical glass vessel, ideal for conducting controlled experiments under laboratory-scale conditions. The vessel structure allows easy handling ...
Jacketed Glass Reactor LJGR-T2041
Jacketed Glass Reactor features a 5 body rotation supports safe content transfer and minimises physical effort during cleaning. Its overhead frame holds components securely and allows ve...
Jacketed Glass Reactor LJGR-T2040
Jacketed Glass Reactor features a 100 L cylindrical glass vessel, ideal for pilot-scale chemical workflows and lab-scale trials. The handwheel rotation allows safe vessel tilting for eas...
Jacketed Glass Reactor LJGR-T2039
Jacketed Glass Reactor features a 50 L cylindrical glass vessel, ideal for reactions under varied temperature conditions. The condenser unit improves vapour recovery, ensuring stable out...
Jacketed Glass Reactor LJGR-T2038
Jacketed Glass Reactor features a 20 jacket supports controlled temperature circulation to maintain stable reactions. Our reactor is used for synthesis, distillation, and concentration i...
Jacketed Glass Reactor LJGR-T2037
Jacketed Glass Reactor features a 10 reactions and thermal processes. It includes an overhead lifting design that improves access during setup and cleaning. The hand wheel allows the ves...
Jacketed Glass Reactor LJGR-T2036
Jacketed Glass Reactor features a 5 use. Its stirring motor provides uniform agitation, ensuring consistent mixing during experiments. The lifting system allows vertical adjustment of th...
Jacketed Glass Reactor LJGR-T2035
Jacketed Glass Reactor features a 200 chemical processes with effective temperature control. It includes a receiving bottle to enable continuous collection during extended reactions. The...
Jacketed Glass Reactor LJGR-T2034
Jacketed Glass Reactor comes with a 150 reactions and stable thermal control. The built-in dropping funnel supports consistent reagent transfer without disturbing internal activity. Its ...
Jacketed Glass Reactor LJGR-T2033
Jacketed Glass Reactor with a 100 reactions with steady thermal control. Its jacketed design circulates fluid through the outer layer to manage temperature during operation. The stirrer ...
Jacketed Glass Reactor LJGR-T2032
Jacketed Glass Reactor features a 50 L cylindrical vessel that offers ample volume for bulk reactions and supports even thermal distribution throughout the contents. Its wide neck and ac...
Jacketed Glass Reactor LJGR-T2031
Jacketed Glass Reactor features a 30 L cylindrical vessel that supports medium-scale reactions with efficient heat transfer and mixing. It ensures uniform temperature control throughout ...
Jacketed Glass Reactor LJGR-T2030
Jacketed Glass Reactor has a 20 L vessel, suitable for medium-scale synthesis, distillation with consistent mixing performance in laboratory use. Its dual-seal design maintains stable re...
Jacketed Glass Reactor LJGR-T2029
Jacketed Glass Reactor features a 10 experimentation. This laboratory glass reactor is designed to meet the rigorous requirements of modern laboratory operations, ensuring high precision...
Jacketed Glass Reactor LJGR-T2028
Jacketed Glass Reactor a 200 chemical processes requiring controlled environments. The chemical spill protection tray effectively contains accidental leaks, helping maintain a clean work...
Jacketed Glass Reactor LJGR-T2027
Jacketed Glass Reactor features a 150 reactions in synthesis, distillation, and concentration. The wide vessel lid offers easy access for adding materials and inserting instruments. Its ...
Jacketed Glass Reactor LJGR-T2026
Jacketed Glass Reactor features a 100 experiments requiring consistent thermal control. Its wide lid design simplifies reagent loading and internal maintenance. The built-in vacuum funct...
Jacketed Glass Reactor LJGR-T2025
Jacketed Glass Reactor includes a 50 experimental work. Its quick-release clamps support faster setup and removal, minimizing delays. A stable support frame reduces vibration and maintai...
Jacketed Glass Reactor LJGR-T2024
Jacketed Glass Reactor features a 30 chemical experiments with structural reliability and clear visibility. Its broad temperature range allows both heating and cooling, adapting to diver...
Jacketed Glass Reactor LJGR-T2023
Jacketed Glass Reactor includes a 20 L cylindrical glass vessel designed to handle large sample volumes for material synthesis. The integrated stirring system provides consistent agitati...
Jacketed Glass Reactor LJGR-T2022
Jacketed Glass Reactor includes a 10 and petroleum fields. This laboratory glass reactor is designed to meet the rigorous requirements of modern laboratory operations, ensuring high prec...
Jacketed Glass Reactor LJGR-T2021
Jacketed Glass Reactor with a 5 operation. Our Reactor supports material synthesis, distillation, and concentration across pharmaceutical, chemical, and academic research. This laborator...
Jacketed Glass Reactor LJGR-T2020
Jacketed Glass Reactor with a 3 jacket. It performs reliably under varying thermal conditions to support diverse laboratory processes. The integrated condenser improves operational stabi...
Standards
ISO 3585:1998-Borosilicate glass 3.3-Properties
Complies with the above standards, but is not limited to them.
Features
1. Jacketed glass reactor for controlled chemical synthesis with heating/cooling circulation through glass jacket.
2. Double-walled glass vessel with overhead stirrer, reflux condenser, addition funnel, and temperature control.
3. Suitable for chemical, pharmaceutical, biotech, food, cosmetic and research laboratories for synthesis and scale-up.
4. Includes glass vessel (jacketed), overhead stirrer, condenser, feed tank, temperature probe, stand and manual.
5. Supports batch reactions under vacuum/pressure, heating/cooling, distillation, reflux, extraction and crystallization.
FAQ
Q1: What testing scenarios is this reactor mainly applied to?
A: The jacketed glass reactor is used in chemical, pharmaceutical, biotechnology, food, cosmetic, and research laboratories for controlled chemical reactions, synthesis, and process scale-up, where the double-walled glass jacket allows circulation of heating or cooling fluid (oil/water) to precisely control reaction temperature, while the transparent glass allows visual monitoring of the reaction. It supports chemical synthesis (organic synthesis, polymerization, condensation, oxidation, reduction, Grignard reactions, hydrolysis, esterification - controlled temperature, stirring, reagent addition under inert atmosphere), pharmaceutical (API (active pharmaceutical ingredient) synthesis and scale-up, crystallization, salt formation, solvent recovery, process development (lab to pilot scale), cGMP production), biotechnology (cell culture (if suitable), fermentation, enzyme reactions, protein precipitation, bioconversion), food and beverage (flavor extraction, essential oil distillation, reaction of food-grade ingredients, crystallization of sugars/sweeteners), cosmetic and personal care (emulsion preparation, cream/lotion synthesis, fragrance extraction, surfactant reactions), chemical process development (optimization of reaction parameters (temp, time, stoichiometry, stirring speed), scale-up from lab (1-5 L) to pilot (10-100 L), kinetic studies), and academic/research (teaching, research, method development). The jacketed design: inner vessel holds reaction mixture; outer jacket circulates heat transfer fluid (thermal oil for heating to 200-250 degrees C, or coolant/ethylene glycol for cooling to -20 to -80 degrees C with chiller). This allows precise temperature control (often +/- 0.5 degrees C) and rapid heating/cooling. Glass (borosilicate 3.3) is chemically resistant and transparent, allowing visual inspection. Typically operates at atmospheric pressure or mild vacuum (for distillation/degassing); some models handle slight positive pressure. Overhead stirrer provides mixing (anchor, paddle, or PTFE stirrer). Accessories: reflux condenser (for volatile solvents), addition funnel (controlled reagent addition), thermometer/thermowell, vacuum port, inert gas (N2/Ar) inlet, discharge valve at bottom.
Q2: What standards does the reactor comply with?
A: The jacketed glass reactor follows relevant ISO, ASTM, IEC, FDA and GB/T standards including ISO 1778 (laboratory glassware - general purpose), ISO 3585 (borosilicate glass 3.3 - properties), ISO 4793 (laboratory sintered glass filters), ASTM E438 (standard specification for glasses in laboratory apparatus - type I class A (borosilicate)), IEC 61010 (laboratory electrical equipment safety - for stirrer/temperature controller), FDA 21 CFR (if pharmaceutical/food contact - glass is generally recognized as safe (GRAS) for food/pharma), and GB/T standards for glass reactors and laboratory glassware. The hardware complies with pressure/vacuum ratings (glass vessels have specific pressure limits - typically full vacuum to slight positive pressure; do not exceed manufacturer rating), glass quality (borosilicate 3.3 per ISO 3585/ASTM E438), and electrical safety (stirrer, temperature controller per IEC 61010). For pharmaceutical use, follow cGMP (21 CFR Part 211), equipment qualification (IQ/OQ/PQ), and material traceability (glass certificates, stirrer material certificates (PTFE, stainless steel 316L)). For food use, follow FDA food contact regulations and applicable food-grade standards. For pressure operation, follow pressure vessel safety (though glass reactors are typically not for high pressure - use autoclave for pressure reactions). For solvent use, follow fire/explosion safety (flammable solvents require spark-free equipment, fume hood, inert atmosphere). For regulated industries, maintain calibration records (temperature probe, stirrer speed) and equipment logs.
Q3: What is the warranty period for the whole reactor and key components?
A: The whole jacketed glass reactor is covered by a 12-24 month warranty (lab equipment often 1-2 years; glass may have shorter warranty due to fragility). The stand, overhead stirrer motor, temperature controller, and metal fittings are covered, while glass vessel (wear/breakable - glass can crack from thermal shock, impact, overpressure; handle carefully; some warranty excludes glass breakage), seals/gaskets (PTFE, silicone - wear from chemical attack/heat, replace periodically), stirrer shaft/blade (wear, especially PTFE coating), and hoses (for jacket fluid - wear from heat/chemicals) are consumables/accessories. Damage from improper use, thermal shock (rapid temperature change - hot glass + cold coolant = crack; always heat/cool gradually), overpressure (exceeding glass pressure rating - can implode/explode), dropping/impact (glass is fragile), using incompatible chemicals (HF attacks glass; strong bases at high temp etch borosilicate), dry heating (no fluid in jacket while heating - cracks glass), or unauthorized repair is excluded. Extended warranty and service contracts (preventive maintenance, calibration) may be available. Glass vessel lifespan: 3-10 years with proper care (but can break anytime from misuse/accident); stirrer motor 5-10 years; seals 1-3 years.
Q4: Is this device difficult to operate? Is professional training required?
A: Operation requires trained chemistry/lab personnel (familiar with chemical reactions, glassware, hazardous materials, temperature control). We provide operation manuals, installation, and training (typically 1-3 days). Proper setup (place reactor on stable, level bench or floor stand (large reactors need floor stand), assemble glass components (vessel, lid, condenser, addition funnel, stirrer) using proper clamps and supports (glass must not be under stress - leave room for thermal expansion), connect jacket hoses to heating/circulator (inlet/outlet; ensure no air locks in jacket - bleed air), connect overhead stirrer (secure shaft, ensure blade does not touch vessel bottom/walls; adjust height), connect temperature probe (thermowell with heat transfer fluid or direct probe; ensure probe is in reaction mixture, not touching vessel), connect vacuum/inert gas (if needed), connect cooling water to condenser (if reflux/distillation), verify all connections are tight and clamps secure), pre-operation checks (inspect glass for cracks/stars (do not use cracked glass - can fail catastrophically), verify jacket fluid level in circulator, ensure stirrer rotates freely (no binding), check seals/gaskets for damage, ensure emergency stop accessible, have spill kit/eyewash nearby), operation (add reactants/solvent through top port or addition funnel (do not fill >2/3 of vessel volume - leave headspace for boiling/foaming), start stirrer (set speed - start low, increase gradually; avoid splashing), start jacket circulation (set temperature - heat/cool gradually to avoid thermal shock; monitor temperature), add reagents via addition funnel at controlled rate (for exothermic reactions, add slowly with cooling; monitor temp), maintain inert atmosphere (N2/Ar) if air/moisture sensitive, monitor reaction (visually through glass, via temperature, sampling (use sampling valve or syringe), TLC/HPLC), for distillation: set up condenser, receiver, vacuum; for reflux: condenser with coolant, post-operation (stop heating, allow cooling (gradual - do not shock with cold coolant while glass is hot), stop stirrer, release vacuum/inert gas carefully, discharge product via bottom valve (if equipped) or pour out, clean reactor (rinse with appropriate solvent, then water/detergent; remove glass components for thorough cleaning; do not use abrasive brushes on glass (scratches weaken glass); dry thoroughly), maintenance (daily: wipe exterior, check jacket fluid, inspect glass for damage, clean spills immediately; weekly: inspect seals/gaskets (replace if cracked/hardened), check stirrer shaft alignment, lubricate (per manufacturer); monthly: verify temperature probe calibration (with certified thermometer), check stirrer speed, inspect hoses for cracks/leaks; semi-annually/annually: professional maintenance (stirrer motor, controller calibration, pressure/vacuum test of glass vessel), troubleshooting (temperature not reaching setpoint (jacket fluid low, circulator failure, air lock in jacket, insulation poor, exothermic/endothermic reaction overwhelming capacity - check fluid, bleed air, increase circulator capacity), stirrer not rotating (motor failure, shaft binding (touching vessel), overload (viscous mixture - reduce speed, use appropriate blade), seal leak (PTFE/silicone seal worn/chemically attacked, over-tightened, misaligned - replace seal, adjust), glass crack/leak (thermal shock, impact, overpressure, chemical attack (HF, hot base) - STOP immediately, do not use cracked glass (can implode/explode under vacuum/pressure), replace vessel), jacket leak (hose loose/cracked, glass jacket cracked - check hoses, inspect jacket), pressure/vacuum not holding (seal leak, glass crack, fitting loose - check seals, glass, fittings), and safety (GLASS HAZARD (borosilicate glass can break/implode/explode - wear safety glasses/face shield, lab coat, gloves; do not use cracked glass; never exceed pressure/vacuum rating; use blast shield for pressure/vacuum reactions; beware of implosion under vacuum (flying glass)), CHEMICAL HAZARD (reactions may involve flammable, corrosive, toxic, reactive chemicals - use fume hood, appropriate PPE, know SDS, have spill kit/eyewash/shower; exothermic reactions can runaway - use cooling, controlled addition, never leave unattended; pyrophoric/air-sensitive materials require inert atmosphere and special handling), PRESSURE/VACUUM (glass reactors are typically for atmospheric or mild vacuum; do NOT pressurize unless rated; if pressure reaction needed, use metal autoclave; under vacuum, beware of implosion), THERMAL SHOCK (never add cold coolant to hot jacket or hot fluid to cold glass - heat/cool gradually; thermal shock is a major cause of glass breakage), OVERFILLING (do not fill >2/3 - boiling/foaming can overflow, cause pressure), STIRRER (do not start at high speed (splashing, shaft whip); ensure blade does not touch glass (scratches/cracks), do not run dry), ELECTRICAL (stirrer/controller - proper grounding, do not use with wet hands, keep away from solvent vapors (spark hazard)), do not leave reaction unattended (especially exothermic or distillation), for pharma/food: follow cGMP (cleaning validation, batch records, equipment logs), handle glass carefully (support all glass joints, do not stress, use proper clamps)) are critical for safe reactor operation.
Q5: What is the typical lead-time for order delivery?
A: Standard models require 7-30 working days. In-stock units can ship within 3-7 working days. Custom configurations or large built-to-order systems may require additional time, and we confirm the exact schedule before order confirmation.
Q6: Is regular calibration required? What is the recommended calibration cycle?
A: Calibration/performance verification recommended every 6-12 months (or per quality system): temperature probe calibration (with certified thermometer traceable to national standards; verify at multiple points across range (e.g., 0, 50, 100, 200 degrees C); accuracy typically +/- 0.5 degrees C), stirrer speed calibration (with tachometer; verify at low/mid/high speeds), and temperature uniformity (jacket vs vessel - verify with multiple probes). If reactor is moved, probe replaced, stirrer serviced, or readings seem off, recalibrate. Routine checks: temperature probe verification before critical reactions (compare with reference thermometer), stirrer speed check, glass inspection (cracks) before each use. For GMP/pharma labs, follow applicable calibration schedules and maintain records (calibration certificates, as-found/as-left data, probe ID, equipment logs). Glass vessel integrity: pressure/vacuum leak test annually or after any impact/repair. Heating/cooling circulator should be calibrated separately (per manufacturer). For pharma cGMP, equipment qualification (IQ/OQ/PQ) is required initially and re-qualification periodically (annually or after major repair).
Q7: Are supporting consumables universal?
A: Seals/gaskets (PTFE, silicone, Viton - specific to reactor joint size (standard ground glass joints: NS 24/40, 29/42, etc.; use appropriate size/material for chemical compatibility), stirrer shaft/blade (specific to reactor size/stirrer; PTFE or 316L), hoses (for jacket fluid - standard rubber/silicone, but use heat-resistant if high temp), glass components (condenser, addition funnel, adapters - standard ground glass joints are somewhat universal (ISO/ASTM joint sizes), but use manufacturer-compatible for proper fit), temperature probe (specific to controller), and cleaning supplies are available from lab supply companies (Chemglass, Ace Glass, VWR, Sigma), though seals and stirrers are often reactor-specific (use OEM or certified compatible with correct dimensions/materials). Long-term consumable cost includes seal/gasket replacement (periodic, $20-$100 per set), stirrer blade (if worn/broken), and occasional glass replacement (if broken - expensive, $500-$5000+ depending on size).
Q8: Can I customize parameters or supporting accessories?
A: Customization includes volume (1 L, 2 L, 5 L, 10 L, 20 L, 50 L, 100 L, 200 L - lab to pilot scale), vessel design (single jacket (heating/cooling), double jacket (insulation + temperature), triple jacket (for extreme temps), cylindrical or spherical bottom, bottom discharge valve), number/type of ports (4-neck, 6-neck lid; ports for stirrer, condenser, addition funnel, thermometer, vacuum, inert gas, sampling, pH probe), stirrer (overhead stirrer with PTFE or 316L shaft; blade type (anchor, paddle, turbine, PTFE); speed range (50-2000 RPM); explosion-proof motor (ATEX) for flammable solvents), temperature control (ambient to 200-250 degrees C heating; -20 to -80 degrees C cooling (with chiller); precision +/- 0.1-0.5 degrees C; digital controller with PID, ramp/soak programming), pressure/vacuum (full vacuum to slight positive pressure (typically -1 to +0.5 bar); do not exceed glass rating; for higher pressure use metal autoclave), materials (borosilicate glass 3.3 vessel; PTFE seals/stirrers (chemical resistance); 316L stainless steel (for parts); silicone/Viton gaskets), accessories (reflux condenser, addition funnel (pressure-equalizing), distillation head, receiver flask, vacuum pump, heating/cooling circulator (oil/water), chiller, inert gas (N2/Ar) setup, pH probe, data logging/software, explosion-proof (ATEX) for hazardous areas, validation package (IQ/OQ/PQ for pharma), certifications (CE, ISO, FDA food contact, ATEX), language and accessories. Additional glassware, circulator, and accessories can be ordered separately.
Q9: Does the purchase include on-site installation and commissioning service?
A: Standard delivery includes jacketed glass reactor (vessel, lid, stirrer, basic accessories), stand, temperature controller, and instruction manual. On-site installation, commissioning, and operator training ARE typically included or strongly recommended for jacketed glass reactors (glass assembly requires proper setup (clamping, alignment, seal installation), heating/cooling circulator integration, leak testing, and user training on safe operation (thermal shock, pressure/vacuum, chemical handling); installation by manufacturer or certified technician is standard, especially for >10 L or automated systems). For small lab reactors (1-5 L): self-assembly is possible with manual guidance, but initial training on safe operation is recommended. Always inspect glass for damage, test for leaks, and verify temperature/stirrer before first use.
Q10: What types of samples are compatible with this equipment?
A: The jacketed glass reactor handles various chemical reactions and materials including organic chemicals (solvents, reagents, monomers, polymers - synthesis, polymerization, distillation, crystallization), pharmaceutical intermediates and APIs (synthesis, crystallization, salt formation, solvent recovery), food-grade ingredients (flavors, fragrances, essential oils, extracts, sugars - distillation, extraction, reaction; use food-grade materials), cosmetics/personal care (emulsions, creams, surfactants, fragrances), and aqueous/organic solutions. Glass (borosilicate 3.3) is compatible with most acids, bases, solvents, and organic compounds. NOT compatible with: Hydrofluoric acid (HF) - etches/attacks glass (use PTFE or plastic vessels), strong bases (NaOH, KOH) at high temperature (>100 degrees C) and high concentration - etches borosilicate over time (use PTFE-lined or limit exposure), very high pressure (>0.5-1 bar positive pressure) - glass is not rated for high pressure (use metal autoclave), extremely rapid temperature changes (thermal shock cracks glass - heat/cool gradually), dry heating (jacket must have circulating fluid when heating; dry heat cracks glass), samples that foam/boil over (do not overfill; use anti-foam, larger vessel, controlled heating), highly exothermic reactions without proper cooling/capacity (can runaway - ensure circulator capacity and controlled addition), and materials that attack PTFE/stirrers (some molten alkali metals, certain fluorinated compounds at high temp - verify compatibility). Also not for: high-temperature molten metals/salts (>250 degrees C, beyond glass/circulator rating), reactions requiring high pressure (use autoclave), and large-scale production (>200 L, use pilot plant glass-lined steel reactors). IMPORTANT: Jacketed glass reactor fundamentals: (1) What it is: A double-walled (jacketed) borosilicate glass vessel used for controlled chemical reactions. The inner vessel holds the reaction mixture; the outer jacket circulates a heat transfer fluid (thermal oil for heating, water/glycol for cooling) to control temperature. Transparent glass allows visual monitoring. Overhead stirrer mixes contents. Various ports allow reagent addition, temperature measurement, condensation, vacuum/inert gas. (2) Key components: - Jacketed vessel: Borosilicate glass 3.3 (chemical resistance, thermal shock resistance, transparent). Inner volume 1-200 L. - Jacket: Circulates heating/cooling fluid. Inlet/outlet ports. Must always have fluid when heating/cooling. - Lid: Multi-neck (4-6 ports) for stirrer, condenser, addition, thermometer, vacuum, gas. - Overhead stirrer: Motor + shaft + blade (PTFE or 316L). Mixes reaction. Speed 50-2000 RPM. - Temperature probe: Thermowell or direct probe. Measures reaction temp. - Condenser: Reflux (returns vapors) or distillation (collects distillate). - Addition funnel: Controlled reagent addition (pressure-equalizing for closed systems). - Vacuum/gas ports: For vacuum distillation, degassing, inert atmosphere (N2/Ar). - Stand: Supports glass vessel (floor or bench). - Heating/cooling circulator: Provides fluid at set temp to jacket (separate equipment). (3) Temperature control: - Heating: Thermal oil (up to 200-250 degrees C) or water (up to 100 C). - Cooling: Water (to ~10 C), ethylene glycol/water (to -20 C), or chiller (to -80 C). - The jacket circulates fluid, controlling vessel wall temp, which controls reaction temp. - Precision: +/- 0.1-0.5 degrees C with PID controller. - Heat/cool GRADUALLY to avoid thermal shock (major cause of glass breakage). (4) Pressure/vacuum: - Typically designed for full vacuum (for distillation, degassing, removing solvents) to slight positive pressure. - NEVER exceed manufacturer pressure rating (glass can explode). - For pressure reactions, use metal autoclave (not glass). - Under vacuum, beware of IMPLOSION (glass shatters inward, flying debris) - use blast shield, face shield. (5) Common reactions/applications: - Organic synthesis (condensation, oxidation, reduction, polymerization, Grignard, etc.) - Crystallization (controlled cooling, seeding) - Distillation (simple, fractional, vacuum, steam) - Reflux (heating with condenser to retain volatile solvent) - Extraction (liquid-liquid, solid-liquid) - Emulsion/cream preparation (cosmetics, pharma) - Fermentation/bioconversion (if temp controlled, sterile) - Process scale-up (lab 1L -> pilot 50-100L) (6) Safety (critical for glass reactors): - Thermal shock: #1 cause of breakage. Never put cold coolant in hot jacket or hot fluid in cold vessel. Heat/cool gradually (<5 degrees C/min). - Glass breakage: Inspect before each use (cracks, stars). Do not use damaged glass. Support properly (no stress on joints). - Pressure/vacuum: Never exceed rating. Use blast shield. Under vacuum = implosion risk. - Chemical compatibility: HF attacks glass. Hot strong bases etch glass. Verify all materials (glass, PTFE, seals) with chemicals. - Overfilling: Max 2/3 volume (boiling/foaming). - Exothermic reactions: Can runaway. Use cooling, controlled addition, monitoring. Never leave unattended. - Flammable solvents: Use fume hood, spark-free (explosion-proof) stirrer, no open flame, inert atmosphere. - Stirrer: Do not let blade touch glass (scratches/cracks). Start at low speed. - Cleaning: Do not use abrasive brushes (scratches weaken glass). Rinse with solvent then water. Dry thoroughly. (7) Jacketed vs non-jacketed: - Jacketed: Precise temp control via circulating fluid, faster heating/cooling, can heat and cool. For controlled reactions. - Non-jacketed (single wall): Heated via heating mantle or oil bath. Less precise, slower. Simple, cheaper. - For process development and scale-up, jacketed is preferred. (8) Choosing the right reactor: - Volume: 1-5 L for lab research, 10-50 L for pilot, 100-200 L for scale-up. - Temp range: Ambient to 200 C standard; low temp (-80 C) needs chiller. - Pressure: Atmospheric/vacuum standard; high pressure needs autoclave. - Automation: Manual (basic) vs automated (software, data logging, recipe control) for GMP/scale-up. - Hazardous location: Explosion-proof (ATEX) for flammable solvents. - Material: Borosilicate glass standard; PTFE-lined for HF/bases.
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