Liquid Chromatography Mass Spectrometry (LC-MS)

Introduction

Liquid Chromatography-Mass Spectrometry (LC-MS) is a powerful analytical technique used in chemistry and biology. LC separates complex mixtures of compounds, and MS identifies and quantifies them. In LC, a liquid mobile phase carries the sample through a column, separating components based on their chemical properties. The eluent then enters the MS, where ions are generated, and their mass-to-charge ratios are measured. By comparing mass spectra with known standards, LC-MS identifies compounds with high sensitivity and specificity. It is widely applied in drug discovery, environmental analysis, and metabolomics, providing invaluable insights into complex mixtures.

Standards

USP General Chapter <621>-Chromatography

European Pharmacopoeia 2.2.46-Chromatographic separation techniques

WHO TRS 1025 Annex 4-Good chromatography practices

Complies with the above standards, but is not limited to them.

Features

1. Precise injector, column and detector separate complex mixtures.

2. Choice of detectors suits different compounds and sensitivities.

3. Automated sampler improves throughput and precision.

4. GC, HPLC and modular configurations cover many applications.

5. Gas and temperature safety interlocks protect the system.

FAQ

What is the Liquid Chromatography Mass Spectrometry (LC-MS) mainly used for?

The Liquid Chromatography Mass Spectrometry (LC-MS) is used to separate, identify and quantify components in a mixture. It supports chemical analysis, quality control, environmental testing, food safety and pharmaceutical work requiring selective detection.

What standards does the Liquid Chromatography Mass Spectrometry (LC-MS) comply with?

The instrument is designed with reference to IEC 61010 electrical safety, applicable chromatography standards and relevant GB/T methods. Columns and procedures should follow validated methods. Compliance documentation can be provided on request.

What warranty comes with the Liquid Chromatography Mass Spectrometry (LC-MS)?

The complete unit carries a 12-month warranty from delivery, covering the main body, core components and controller against manufacturing defects. Consumables and wearing parts such as filters, seals and probes are not covered. Damage from misuse, improper power or unauthorised repair is excluded, and extended warranty can be quoted.

Will staff need special training?

Day-to-day use is simple, with clear prompts and pre-set functions reducing manual steps. New operators should review the manual and complete a short familiarisation. Our technical team offers remote support during the first runs.

How long does delivery usually take?

Standard models require 7-30 working days. In-stock units can ship within 3-7 working days. Custom configurations or large built-to-order systems may require additional time, and we confirm the exact schedule before order confirmation.

Does the Liquid Chromatography Mass Spectrometry (LC-MS) need calibration or verification?

To protect result reliability, periodic verification should be performed, typically once or twice a year. The instrument arrives factory-calibrated, and self-check routines help spot drift. We offer traceable calibration service if the site needs it.

Are consumables and spare parts easy to obtain?

The instrument uses standard, widely available consumables rather than special locked items. Replacement parts, accessories and consumables can be ordered from us against the model number. We keep common service parts in stock for prompt supply.

Are options or configurations available?

Yes, common options include different ranges, voltages, accessories, interfaces and capacity or size configurations. We confirm feasibility, specifications and any delivery impact before order confirmation. Custom requirements are reviewed case by case.

How is the Liquid Chromatography Mass Spectrometry (LC-MS) commissioned?

Most models can be commissioned by following the manual, including positioning, connections, checks and a first test run. Remote guidance is available during start-up. On-site installation, commissioning and training can be arranged separately where required.

What should be avoided when using the Liquid Chromatography Mass Spectrometry (LC-MS)?

Do not use incompatible gases or solvents, block gas paths or run without carrier gas. Handle columns and detectors per their limits. Follow laboratory safety rules.