Glass Fermenter LGF-T2011

Introduction

Glass Fermenter features a 10 L working volume, ideal for pilot-scale mammalian cell culture. Its double-jacketed borosilicate glass vessel ensures uniform thermal regulation, critical for maintaining fragile cell lines. The system employs top-driven mechanical agitation with a low-shear marine impeller to provide consistent mixing without compromising cell integrity. Siemens automation supports real-time control and accurate parameter tracking. Our Glass Fermenter is widely utilized in monoclonal antibody production, gene therapy vector development, and clinical-grade vaccine manufacturing.

This fermenter is designed to meet the rigorous requirements of modern laboratory operations, ensuring high precision, reliability, and ease of use for various experimental applications.

Applications

Our Glass Fermenter is best suited for scale-up of mammalian cell cultures, monoclonal antibody production, and gene therapy process development. It is particularly effective for maintaining the viability of delicate cell lines such as and HEK293, which require gentle agitation and stable environmental conditions for optimal growth and productivity.

Specifications

Working Volume	10 L
Vessel Material	Borosilicate glass (double-jacketed)
Control System	Siemens with 10.4-inch touchscreen
Agitation Type	Top-driven mechanical
Impeller Type	Low-shear marine impeller
Agitation Speed	30 to 300 rpm
Temperature Range	5°C above ambient to 60°C
Temperature Accuracy	±0.1°C
pH Range	2.0 to 12.0
DO Range	0 to 150%
Gas Supply	Air, O₂, CO₂, N₂ (4-gas)
Sterilization	Autoclavable
Data Output	& export

Features

Smart touchscreen-based control system

Multiple sampling, feed, and gas input ports

Compatible with batch, fed-batch, and perfusion modes

4-gas mixing with precise flow regulation

-aligned design and autoclavable vessel

Remote monitoring via software

FAQs

1. What is the working volume range of the fermenter?

The supports a working volume of 5 to 10 liters, making it ideal for pilot-scale mammalian cell culture and bioprocess development.

2. Is the suitable for sensitive cell lines like and HEK293?

Yes, it is specifically designed with low-shear agitation and precise environmental controls, making it highly suitable for fragile cell lines such as and HEK293.

3. What type of control system does use?

is equipped with a Siemens -based control system, allowing real-time monitoring and automated control of key parameters like pH, DO, temperature, and gas flow.

4. Can be integrated into an upstream bioproduction pipeline?

Absolutely. The is designed for seamless integration into upstream workflows for biologics, gene therapies, and vaccine production.

5. What safety and sterility features are included in ?

includes a double-jacketed borosilicate glass vessel, sterile sampling ports, and automated control loops to maintain aseptic conditions and minimize contamination risks during operation.

6. What are the advantages of using a glass fermenter?

Glass fermenters provide excellent visibility, making them ideal for observing microbial or cell culture processes in real time. They are chemically resistant, easy to sterilize, and perfect for research, teaching, and small-scale fermentation experiments.

7. Are glass fermenters autoclavable?

Yes, glass fermenters are made from high-grade borosilicate glass and are fully autoclavable. This ensures contamination-free operation and easy sterilization between experiments.

8. What volumes are available for glass fermenters?

It offers glass fermenters in a variety of working volumes, ranging from small benchtop models for lab-scale research to larger pilot-scale systems. Custom volume configurations are also available based on user requirements.

9. Can I integrate sensors and automation systems with glass fermenters?

Absolutely. glass fermenters support integration with advanced sensors for pH, dissolved oxygen (DO), temperature, and agitation control. They are compatible with digital control systems for automated and real-time bioprocess monitoring.

10. What industries typically use glass fermenters?

Glass fermenters are widely used in academic research, biotechnology, pharmaceuticals, and food industries. Their precision, transparency, and scalability make them ideal for experimental setups, product development, and training environments.