Introduction
A single layer glass reactor is a laboratory reactor with a single-layer glass vessel, used for the chemical reactions, the synthesis, the distillation, and the extraction under the controlled conditions, and it is used in the chemistry, the pharmaceutical, the chemical engineering, and the research laboratories. The single layer glass reactor consists of a glass vessel with the reaction capacity, a stirring system, a heating and a cooling system, which heats or cools the vessel by the electric heating or the bath, and a reflux condenser, and the inlets and the outlets for the addition of the materials and the sampling, and it provides the controlled conditions for the reactions, such as the temperature, the stirring, and the reflux, with features such as the adjustable stirring speed, the temperature control, and the vacuum connection; the single layer glass reactor is used for the chemical synthesis, for the reactions at the controlled temperature, for the distillation and the reflux, for the extraction, for the crystallization, for the preparation of the products, and for many other applications, and it is available in various capacities, from the small laboratory models to the larger models, with the various stirring and the heating configurations; the single layer glass reactor is an essential instrument for the reactions in the laboratory. Single layer glass reactors are used in the chemistry laboratories, in the pharmaceutical industry, in the chemical engineering, in the research institutions, and for many other applications. With their glass vessel, single layer glass reactors are essential for the laboratory reactions.
Single Layer Glass Reactor LSGR-T2020
It is the supplier of Single with stirring speed up to 280 rpm for uniform mixing. The vacuum degree reaches 0.0098 Mpa enabling effective evaporation performance. This laboratory glass ...
Single Layer Glass Reactor LSGR-T2019
Single features a 100 chemical reactions with uniform heating. Its design ensures stable vacuum performance for consistent evaporation and reactions under reduced pressure. The ceramic m...
Single Layer Glass Reactor LSGR-T2018
Single features a 100 experiments. It uses stepless speed control to adjust stirring intensity according to the nature of the reaction. Our Glass Reactor supports various applications in...
Single Layer Glass Reactor LSGR-T2017
Single features a 50-liter vessel, ideal for handling larger sample volumes in lab-scale synthesis. The integrated drain valve allows easy material discharge without tilting. Its reinfor...
Single Layer Glass Reactor LSGR-T2016
Single features a 30 chemical processes. Its durable construction allows for long-lasting performance in demanding environments. The reactor is equipped with advanced an efficient conden...
Single Layer Glass Reactor LSGR-T2015
Single features a 20 L glass vessel volume, offering capacity for various lab-scale reactions. The integrated dropping funnel allows controlled reagent addition, minimizing pressure shif...
Single Layer Glass Reactor LSGR-T2014
Single features a 10 operation, enhancing process reliability. The pressure control system allows stable adjustments during vacuum applications, improving process efficiency. Our Glass R...
Single Layer Glass Reactor LSGR-T2013
Single features a 5 applications. This laboratory glass reactor is designed to meet the rigorous requirements of modern laboratory operations, ensuring high precision, reliability, and ...
Single Layer Glass Reactor LSGR-T2012
Single features a 3-liter glass vessel that provides efficient thermal distribution for optimal reaction conditions. The stirring mechanism of the unit operates smoothly across a wide sp...
Single Layer Glass Reactor LSGR-T2011
Single features a 2L glass vessel that supports controlled chemical reactions with efficient heat distribution. It delivers consistent thermal distribution to support stable reaction con...
Single Layer Glass Reactor LSGR-T2010
Single features a 1L glass vessel, providing efficient temperature control for various reactions. Its high-performance sealing system maintains consistent vacuum levels, minimizing conta...
Standards
ISO 3585:1998-Borosilicate glass 3.3-Properties
Complies with the above standards, but is not limited to them.
Features
1. Single layer glass reactor for chemical synthesis, distillation and reflux with transparent borosilicate glass vessel.
2. Single-walled glass reactor with overhead stirrer, heating mantle or oil bath, condenser and temperature control.
3. Suitable for chemical, pharmaceutical, biotech, food, cosmetic and research laboratories for synthesis and scale-up.
4. Includes glass vessel, overhead stirrer, condenser, feed tank, temperature probe, stand and operation manual.
5. Supports batch reactions, distillation, reflux, extraction and crystallization with direct heating (mantle/oil bath) up to 250 C.
FAQ
Q1: What testing scenarios is this reactor mainly applied to?
A: The single layer (single-walled) glass reactor is used in chemical, pharmaceutical, biotechnology, food, cosmetic, and research laboratories for chemical reactions, synthesis, distillation, and process development, where a single-walled borosilicate glass vessel is heated directly (via heating mantle or oil bath) rather than through a jacket, providing a simple, economical system for reactions requiring heating and stirring. It supports chemical synthesis (organic synthesis, polymerization, condensation, oxidation, reduction, hydrolysis, esterification, Grignard reactions - controlled temperature, stirring, reagent addition under inert atmosphere; glass is inert to most chemicals), pharmaceutical (API synthesis and scale-up, crystallization, salt formation, solvent recovery, process development (lab to pilot), cGMP production; glass is cleanable, non-contaminating), biotechnology (cell culture (if suitable), fermentation, enzyme reactions, protein precipitation, bioconversion), food and beverage (flavor extraction, essential oil distillation, reaction of food-grade ingredients, crystallization of sugars/sweeteners), cosmetic and personal care (emulsion preparation, cream/lotion synthesis, fragrance extraction, surfactant reactions), chemical process development (optimization of reaction parameters, scale-up from lab (1-5 L) to pilot (10-100 L), kinetic studies), and academic/research (teaching, research, method development). Single layer vs jacketed (3296, 3284): Single-walled reactor has one glass wall, heated externally by heating mantle or oil bath. Simpler, cheaper, no circulator needed, but temperature control is less precise (heating mantle has hotspots, slower response, no active cooling) and no built-in cooling. Jacketed reactor has double wall with circulating fluid - more precise temp control, can heat AND cool, but more expensive and requires heating/cooling circulator. Single layer is suitable for reactions where precise temperature control is not critical, or where cooling is not needed (e.g., simple reflux, distillation, heating to set point). For exothermic reactions or precise temp control, jacketed is preferred. Borosilicate glass 3.3 provides chemical resistance and transparency. Typically operates at atmospheric pressure or mild vacuum (for distillation/degassing). Overhead stirrer provides mixing. Accessories: reflux condenser, addition funnel, thermometer, vacuum port, inert gas inlet. See 3296 and 3284 for detailed reactor application, standards, operation, and safety - this entry focuses on single-layer specifics (direct heating, no jacket).
Q2: What standards does the reactor comply with?
A: The single layer glass reactor follows relevant ISO, ASTM, IEC, FDA and GB/T standards including ISO 3585 (borosilicate glass 3.3 - properties), ISO 1778 (laboratory glassware - general purpose), ASTM E438 (standard specification for glasses in laboratory apparatus - type I class A (borosilicate)), IEC 61010 (laboratory electrical equipment safety - for stirrer/heating mantle/temperature controller), FDA 21 CFR (if pharmaceutical/food contact - borosilicate glass is GRAS), and GB/T standards for laboratory glassware and glass reactors. The hardware complies with glass quality (borosilicate 3.3 per ISO 3585/ASTM E438), pressure/vacuum ratings (glass vessels have specific limits - typically full vacuum to slight positive pressure; do not exceed), and electrical safety (stirrer, heating mantle, controller per IEC 61010). For pharmaceutical use, follow cGMP (21 CFR Part 211), equipment qualification (IQ/OQ/PQ), and material traceability (glass certificates, stirrer material certificates (PTFE, 316L)). For food use, follow FDA food contact regulations. For pressure operation, follow pressure vessel safety (glass is typically not for high pressure - use autoclave). For solvent use, follow fire/explosion safety. For regulated industries, maintain calibration records (temperature probe, stirrer speed) and equipment logs. Heating mantle should comply with IEC 61010 and have over-temperature protection. See 3296/3284 for detailed standards.
Q3: What is the warranty period for the whole reactor and key components?
A: The whole single layer glass reactor is covered by a 12-24 month warranty (lab equipment often 1-2 years; glass may have shorter warranty due to fragility). The stand, overhead stirrer motor, temperature controller, heating mantle (if included), and metal fittings are covered, while glass vessel (wear/breakable - borosilicate is durable but can crack from thermal shock, impact, overpressure; handle carefully; some warranty excludes glass breakage), seals/gaskets (PTFE, silicone - wear from chemical attack/heat, replace periodically), stirrer shaft/blade (wear, especially PTFE coating), and heating mantle (wear - element can burn out, fabric can tear) are consumables/accessories. Damage from improper use, thermal shock (rapid temperature change - hot glass + cold liquid = crack; always heat/cool gradually; heating mantle can create hotspots), overpressure (exceeding glass rating - can implode/explode), dropping/impact (glass is fragile), using incompatible chemicals (HF attacks glass; strong bases at high temp etch borosilicate), dry heating with mantle (no liquid in vessel while heating - can overheat glass), heating mantle contact with cold water (can crack mantle/glass), or unauthorized repair is excluded. Extended warranty and service contracts (preventive maintenance, calibration) may be available. Glass vessel lifespan: 3-10 years with proper care; stirrer motor 5-10 years; heating mantle 2-5 years (elements burn out); seals 1-3 years. See 3296/3284 for detailed warranty.
Q4: Is this device difficult to operate? Is professional training required?
A: Operation requires trained chemistry/lab personnel (familiar with chemical reactions, glassware, hazardous materials, heating). We provide operation manuals, installation, and training (typically 1-3 days). Proper setup (place reactor on stable, level bench or floor stand, assemble glass components (vessel, lid, condenser, addition funnel, stirrer) using proper clamps/supports (glass must not be under stress), place heating mantle around vessel (for mantle heating) or position vessel in oil bath (for oil bath heating; ensure oil level covers vessel contents but not above vessel rim), connect overhead stirrer (secure shaft, ensure blade does not touch vessel bottom/walls), connect temperature probe (thermowell or direct probe; ensure probe is in reaction mixture), connect vacuum/inert gas (if needed), connect cooling water to condenser (if reflux/distillation), verify all connections tight), pre-operation checks (inspect glass for cracks/stars (do not use cracked glass), verify heating mantle (no frayed wires, element intact), ensure stirrer rotates freely, check seals/gaskets, ensure emergency stop accessible, have spill kit/eyewash nearby), operation (add reactants/solvent (do not fill >2/3 volume), start stirrer (low speed, increase gradually), start heating (set mantle or oil bath temperature - heat gradually; monitor reaction temperature (not just mantle temp - mantle temp can be much higher than reaction temp; for precise control use thermowell in reaction mixture), add reagents via addition funnel at controlled rate (for exothermic reactions, add slowly with cooling (ice bath or reduce heating; single layer has no active cooling - use external ice bath or slow addition), maintain inert atmosphere (N2/Ar) if air/moisture sensitive, monitor reaction (visually through glass, via temperature, sampling), for distillation: set up condenser, receiver, vacuum; for reflux: condenser with coolant), post-operation (turn off heating, allow cooling (gradual - do not shock with cold water while glass is hot; remove mantle or let oil bath cool), stop stirrer, release vacuum/inert gas carefully, discharge product, clean reactor (rinse with appropriate solvent, then water/detergent; do not use abrasive brushes on glass; dry thoroughly), maintenance (daily: wipe exterior, check heating mantle, inspect glass; weekly: inspect seals/gaskets, check stirrer alignment; monthly: verify temperature probe calibration, check heating mantle element resistance; semi-annually/annually: professional maintenance (stirrer motor, controller calibration, pressure/vacuum test of glass vessel, heating mantle replacement), troubleshooting (temperature not reaching (heating mantle failure (element burned out), controller fault, power issue, insulation poor (mantle not fitting vessel), reaction endothermic overwhelming mantle - check mantle, service, use properly sized mantle, increase power), stirrer not rotating (motor failure, shaft binding (touching vessel), overload (viscous mixture) - reduce speed, use appropriate blade, service), seal leak (PTFE/silicone seal worn/chemically attacked, over-tightened, misaligned - replace seal, adjust), glass crack/leak (thermal shock (rapid temp change, cold water on hot glass), impact, overpressure, chemical attack (HF, hot base) - STOP, do not use cracked glass, replace vessel), heating mantle overheating (thermostat failure, no liquid in vessel (dry heating), mantle too large - service, ensure liquid, use proper size mantle), and safety (GLASS HAZARD (borosilicate glass can break/implode/explode - wear safety glasses/face shield, lab coat, gloves; do not use cracked glass; never exceed pressure/vacuum rating; use blast shield for pressure/vacuum reactions; thermal shock is main risk with single layer (heating mantle creates hotspots, adding cold liquid to hot vessel - heat/cool gradually), HEATING MANTLE HAZARD (mantle gets very hot (surface can exceed 400 C) - burn hazard; do not touch hot mantle; ensure no flammables near; do not run dry (no liquid in vessel) - mantle can overheat and fail; use properly sized mantle (fits vessel); do not submerge mantle in water), CHEMICAL HAZARD (reactions may involve flammable, corrosive, toxic chemicals - fume hood, PPE, know SDS; exothermic reactions can runaway - single layer has no active cooling, use ice bath or slow addition; never leave unattended), PRESSURE/VACUUM (glass for atmospheric/mild vacuum only; do NOT pressurize; under vacuum beware implosion), OVERFILLING (max 2/3 volume), STIRRER (do not start high speed; ensure blade does not touch glass), ELECTRICAL (heating mantle and stirrer - proper grounding, keep away from solvent vapors, do not use with wet hands), do not leave reaction unattended (especially exothermic or distillation), for pharma/food: follow cGMP (cleaning validation, batch records), handle glass carefully (support all joints, do not stress), do not use heating mantle with cracked glass (can expose wiring to chemicals), single layer reactors have less precise temp control than jacketed - for critical exothermic reactions, use jacketed reactor with cooling circulator) are critical. See 3296/3284 for detailed reactor safety and operation.
Q5: What is the typical lead-time for order delivery?
A: Standard models require 7-30 working days. In-stock units can ship within 3-7 working days. Custom configurations or large built-to-order systems may require additional time, and we confirm the exact schedule before order confirmation.
Q6: Is regular calibration required? What is the recommended calibration cycle?
A: Calibration/performance verification recommended every 6-12 months: temperature probe calibration (with certified thermometer at multiple points; accuracy +/- 0.5-1 C), stirrer speed calibration (with tachometer), and heating mantle temperature verification (mantle surface vs setpoint - note: mantle temp differs from reaction temp; always use probe in reaction mixture). Routine checks: temperature probe verification before critical reactions, stirrer speed check, glass inspection (cracks) before each use, heating mantle inspection (frayed wires, element condition). For GMP/pharma labs, follow applicable schedules and maintain records (calibration certificates, as-found/as-left data, probe ID, equipment logs). Glass vessel integrity: pressure/vacuum leak test annually or after any impact/repair. Heating mantle should be replaced when element fails or fabric tears. For pharma cGMP, equipment qualification (IQ/OQ/PQ) initially and re-qualification periodically. Single layer reactors rely on external heating (mantle/oil bath) - the heating device should be calibrated separately per manufacturer. See 3296/3284 for detailed calibration.
Q7: Are supporting consumables universal?
A: Seals/gaskets (PTFE, silicone, Viton - specific to reactor joint size (standard ground glass joints NS 24/40, 29/42; use appropriate size/material), stirrer shaft/blade (specific to reactor size/stirrer; PTFE or 316L), heating mantle (specific to vessel size/shape - use properly sized mantle; universal if size matches), glass components (condenser, addition funnel, adapters - standard ground glass joints somewhat universal), temperature probe (specific to controller), and cleaning supplies are available from lab supply companies (Chemglass, Ace Glass, VWR, Sigma), though seals, stirrers, and heating mantles are often reactor-specific (use OEM or certified compatible with correct dimensions/materials). Long-term consumable cost includes seal/gasket replacement (periodic), stirrer blade (if worn/broken), heating mantle replacement (periodic, $100-$500), and occasional glass replacement (if broken - expensive). See 3296/3284 for detailed consumables.
Q8: Can I customize parameters or supporting accessories?
A: Customization includes volume (1 L, 2 L, 5 L, 10 L, 20 L, 50 L, 100 L, 200 L - lab to pilot), vessel design (single wall (this product), cylindrical or spherical bottom, bottom discharge valve), number/type of ports (4-neck, 6-neck lid; ports for stirrer, condenser, addition funnel, thermometer, vacuum, inert gas, sampling, pH probe), heating method (heating mantle (integrated or separate, various sizes, with/without controller), oil bath (separate, for more uniform heating), or no heater (user supplies)), stirrer (overhead stirrer with PTFE or 316L shaft; blade type (anchor, paddle, turbine, PTFE); speed range (50-2000 RPM); explosion-proof motor (ATEX) for flammable solvents), temperature control (ambient to 200-250 C heating (via mantle/oil bath); no active cooling (single layer; for cooling use external ice bath or jacketed reactor); digital controller with PID), pressure/vacuum (full vacuum to slight positive pressure (typically -1 to +0.5 bar); do not exceed glass rating), materials (borosilicate glass 3.3 vessel; PTFE seals/stirrers; 316L stainless steel; silicone/Viton gaskets), accessories (reflux condenser, addition funnel (pressure-equalizing), distillation head, receiver flask, vacuum pump, heating mantle (with controller), oil bath, inert gas (N2/Ar) setup, pH probe, data logging/software, explosion-proof (ATEX), validation package (IQ/OQ/PQ for pharma), certifications (CE, ISO, FDA food contact, ATEX), language and accessories. Additional glassware, heating mantle, and accessories can be ordered separately.
Q9: Does the purchase include on-site installation and commissioning service?
A: Standard delivery includes single layer glass reactor (vessel, lid, stirrer, basic accessories), stand, temperature controller, and instruction manual (heating mantle/oil bath often NOT included - order separately). On-site installation, commissioning, and operator training ARE typically included or strongly recommended for glass reactors (glass assembly requires proper setup (clamping, alignment, seal installation), heating mantle integration, leak testing, and user training on safe operation (thermal shock, pressure/vacuum, chemical handling, heating mantle safety); installation by manufacturer or certified technician is standard, especially for >10 L or automated systems). For small lab reactors (1-5 L): self-assembly is possible with manual guidance, but initial training on safe operation is recommended. Always inspect glass for damage, test for leaks, and verify temperature/stirrer before first use.
Q10: What types of samples are compatible with this equipment?
A: The single layer glass reactor handles various chemical reactions and materials including organic chemicals (solvents, reagents, monomers, polymers - synthesis, polymerization, distillation, crystallization), pharmaceutical intermediates and APIs (synthesis, crystallization, salt formation, solvent recovery), food-grade ingredients (flavors, fragrances, essential oils, extracts, sugars - distillation, extraction, reaction; use food-grade materials), cosmetics/personal care (emulsions, creams, surfactants, fragrances), and aqueous/organic solutions. Borosilicate glass 3.3 is compatible with most acids, solvents, and organic compounds. NOT compatible with: Hydrofluoric acid (HF) - etches/attacks glass (use PTFE or plastic vessels), strong bases (NaOH, KOH) at high temperature (>100 C) and high concentration - etches borosilicate over time (use PTFE-lined or limit exposure), very high pressure (>0.5-1 bar positive pressure) - glass not rated (use metal autoclave), extremely rapid temperature changes (thermal shock cracks glass - heat/cool gradually; single layer with heating mantle is more prone to hotspots than jacketed), dry heating (vessel must have liquid when heating with mantle; dry heat cracks glass), samples that foam/boil over (do not overfill; use anti-foam, larger vessel, controlled heating), highly exothermic reactions without proper cooling/capacity (single layer has no active cooling - use ice bath or slow addition; for critical exothermic reactions use jacketed reactor with cooling circulator), and materials that attack PTFE/stirrers (some molten alkali metals, certain fluorinated compounds at high temp - verify compatibility). Also not for: high-temperature molten metals/salts (>250 C, beyond glass/mantle rating), reactions requiring active cooling below ambient (single layer cannot actively cool - use jacketed reactor with chiller), reactions requiring high pressure (use autoclave), and large-scale production (>200 L, use pilot plant glass-lined steel reactors). IMPORTANT: Single layer vs jacketed glass reactor: (1) Single layer (single-walled): - One glass wall. - Heated externally: heating mantle (fabric/element wrapping vessel) or oil bath (vessel immersed in oil). - Simpler, cheaper, no circulator needed. - Less precise temperature control (mantle has hotspots, slower response, no active cooling). - No built-in cooling (must use external ice bath or reduce heating). - Suitable for: simple reflux, distillation, reactions where precise temp not critical, heating to set point, educational labs. - Limitations: exothermic reactions hard to control, no active cooling, mantle can overheat if dry. (2) Jacketed (double-walled): - Two glass walls; fluid circulates between them. - More precise temp control (+/- 0.5 C), rapid heating/cooling. - Can heat AND cool (via circulator/chiller). - More expensive, requires heating/cooling circulator. - Suitable for: exothermic reactions, precise temp control, crystallization (controlled cooling), distillation, process scale-up. - For critical reactions, jacketed is preferred. (3) Choosing: - If reaction is simple heating/reflux, budget-conscious: single layer. - If reaction is exothermic, needs precise temp control, or needs cooling: jacketed (3296, 3284). - Both use borosilicate glass 3.3, overhead stirrer, condensers, etc. - Safety considerations are similar (glass breakage, thermal shock, pressure/vacuum, chemicals). See 3296 (jacketed glass reactor) and 3284 (borosilicate glass reactor) for detailed reactor fundamentals, safety, and operation - those entries cover the general glass reactor knowledge in depth. This entry focuses on single-layer specific aspects (direct heating, no jacket, heating mantle use).
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