Introduction
A nano spectrophotometer is a specialized spectrophotometer designed to measure the absorbance of very small sample volumes, typically 0.5 to 2 microliters, making it ideal for measuring nucleic acids, proteins, and other biomolecules without the need for cuvettes or dilution, and it is widely used in molecular biology, biochemistry, and genomics laboratories. In operation, a small drop of the sample is placed directly on the measurement surface, often a pedestal or a fiber-optic probe, and the instrument measures the absorbance of the sample over a range of wavelengths, typically from about 200 to 900 nm; the absorbance at specific wavelengths is used to determine the concentration and purity of nucleic acids, using the absorbance at 260 nm for DNA and RNA, and the ratio of absorbance at 260 nm to 280 nm for protein contamination, and the ratio of 260 nm to 230 nm for other contaminants, while protein concentration is measured using absorbance at 280 nm or by colorimetric assays. Nano spectrophotometers provide fast, convenient measurements of small volumes without dilution, preserving precious samples, and they are used for quantifying DNA, RNA, and oligonucleotides, for measuring protein concentration, for checking the purity of nucleic acid preparations, for measuring the concentration of dyes and other molecules, for monitoring purification steps, and for quality control in molecular biology, genomics, and biotechnology laboratories. They are available as benchtop instruments with touch screens or software, and as portable models, with features such as full-spectrum scanning, automatic path length adjustment, and sample recovery. With their micro-volume capability, nano spectrophotometers are essential instruments for nucleic acid and protein quantification.
Nano Spectrophotometer LNS-T2010
Nano Spectrophotometer provides a wavelength range of 180 to 910 nm for versatile sample analysis. It is designed for small-volume samples of 0.5 to 2.0 µL, ideal for high-concentration...
Nano Spectrophotometer LNS-T2011
Nano Spectrophotometer comes with a wavelength range of 180 to 910 nm, designed for a wide range of analytical applications. It delivers fast detection times between 2 and 6 seconds. Wit...
Nano Spectrophotometer LNS-T2012
Nano Spectrophotometer covers a broad wavelength range from 180 to 910 nm, suitable for a diverse array of uses. It comes with an integrated printer, making it easy to print results dire...
Nano Spectrophotometer LNS-T2010
Nano Spectrophotometer offers a detection wavelength range of 190 to 850 nm. It requires only a 0.5-2 μL sample for basic measurements, even for high-concentration samples without dilut...
Nano Spectrophotometer LNS-T2011
Nano Spectrophotometer with full spectrum covers a wide wavelength range of 190 to 850 nm. It requires only 0.3 - 2 µl sample for measurement which takes place within 5 seconds. It uses...
Nano Spectrophotometer LNS-T2010
Nano Spectrophotometer is a compact and table-top unit comprised with UV-silicon photocell detector and UV- light source, offers 260 nm and 280 nm of fixed wavelength range with 0.5 mm o...
Nano Spectrophotometer LNS-T2010
Nano Spectrophotometer with full spectrum covers a wide wavelength range of 190 to 850 nm. It requires only 0.3 - 2 µl sample for measurement which takes place within 5 seconds. It uses...
Nano Spectrophotometer LNS-T2020
Nano Spectrophotometer is a benchtop unit comprises wide wavelength range of 190 to 850 nm, 50 µl micro volume cuvette sample measurement with 8.5 mm sample level height, and 1 mm, 2mm,...
Nano Spectrophotometer LNS-T2013
Nano Spectrophotometer with full spectrum covers a wide wavelength range of 190 to 850 nm. It requires only 0.3 - 2 µl sample for measurement which takes place within 5 seconds. It uses...
Nano Spectrophotometer LNS-T2012
Nano Spectrophotometer with full spectrum covers a wide wavelength range of 190 to 850 nm. It requires only 0.3 - 2 µl sample for measurement which takes place within 3 seconds. Advance...
Nano Spectrophotometer LNS-T2011
Nano Spectrophotometer is micro volume UV spectrophotometer which takes measurements at 230 nm, 260 nm, 280 nm. It utilizes detector, Xenon flash lamp as light source which has high stab...
Nano Spectrophotometer LNS-T2010
Nano Spectrophotometer offers a wavelength range of 200 to 800 nm and supports two path lengths, 0.2 mm for high concentration samples and 1.0 mm for regular measurements. It directly de...
Nano Spectrophotometer LNS-T2021
Nano Spectrophotometer is micro volume UV spectrophotometer which takes measurements at 230 nm, 260 nm, 280 nm. It utilizes detector, Xenon flash lamp as light source which has high stab...
Standards
European Pharmacopoeia 2.2.25-Spectrophotometry, ultraviolet and visible
ASTM E275-08(2022)-Standard Practice for Describing and Measuring Performance of Ultraviolet, Visible, and Near-Infrared Spectrophotometers
Complies with the above standards, but is not limited to them.
Features
1. Nano spectrophotometer for microvolume nucleic acid and protein quantification.
2. Small sample volume (0.5-2uL) with no cuvettes required for rapid measurement.
3. Suitable for molecular biology, genomics, proteomics and clinical research laboratories.
4. Measures DNA, RNA, protein concentration and purity with UV-Vis absorbance.
5. Includes sample pedestal, light source, detector, software and operation manual.
FAQ
Q1: What testing scenarios is this spectrophotometer mainly applied to?
A: The nano spectrophotometer is used in molecular biology, genomics, proteomics, clinical research, pharmaceutical development and biotechnology laboratories to rapidly measure the concentration and purity of nucleic acids (DNA, RNA) and proteins using microvolume UV-Vis absorbance without requiring cuvettes. It supports DNA and RNA quantification for sequencing, PCR and cloning, nucleic acid purity assessment (A260/A280 and A260/A230 ratios), protein concentration measurement (A280, Bradford, BCA), sample quality check before next-generation sequencing, molecular biology experiment setup, and clinical research sample quantification. The microvolume design uses only 0.5-2 microliters of sample, conserving precious samples and eliminating cuvette costs. It is essential for molecular biology, genomics, proteomics and clinical research laboratories requiring rapid, microvolume nucleic acid and protein quantification for sequencing, PCR, cloning, expression studies, sample quality control and experimental setup, where small sample volume, fast measurement, no cuvette requirement and direct concentration calculation are critical for efficient molecular biology workflows, precious sample conservation and high-throughput sample quality assessment in life science and biomedical research applications.
Q2: What standards does the spectrophotometer comply with?
A: The nano spectrophotometer complies with relevant IEC 61010 laboratory electrical safety standards and applicable GB/T standards for UV-Vis spectrophotometers. Molecular biology applications follow good laboratory practice. Calibration should use certified reference standards or validated nucleic acid/protein samples. Wavelength and absorbance accuracy should be verified periodically.
Q3: What is the warranty period for the whole machine and key components?
A: The whole nano spectrophotometer is covered by a 12-month warranty. The light source, detector, optics and software are covered, while sample pedestals, calibration standards and fuses are consumables or accessories. Damage from improper sample handling, scratching the pedestal or unauthorized repair is excluded. Extended service contracts are available.
Q4: Is this device difficult to operate? Is professional training required?
A: Operation requires basic training in molecular biology sample handling, spectrophotometric measurement and data interpretation. We provide an operation manual and remote guidance. Proper sample application, pedestal cleaning, blank measurement and result interpretation are important for accurate quantification, particularly for low-concentration or impure samples.
Q5: What is the typical lead-time for order delivery?
A: Standard models require 7-30 working days. In-stock units can ship within 3-7 working days. Custom configurations or large built-to-order systems may require additional time, and we confirm the exact schedule before order confirmation.
Q6: Is regular calibration required? What is the recommended calibration cycle?
A: Wavelength and absorbance calibration with certified standards recommended every 6-12 months. Routine verification with a reference standard before critical measurements. Sample pedestal condition and cleanliness checked before each use. Light source replacement per usage hours. Full system performance verification annually.
Q7: Are supporting consumables universal?
A: Calibration standards, cleaning supplies and sample pedestals are available from specialized suppliers, though instrument-specific parts should be verified. Long-term consumable cost is low, with no cuvettes required.
Q8: Can I customize parameters or supporting accessories?
A: Customization includes wavelength range, sample volume, detection limit, software features and connectivity. Additional accessories can be ordered separately. Custom orders extend delivery lead-time.
Q9: Does the purchase include on-site installation and commissioning service?
A: Standard delivery includes the nano spectrophotometer and accessories with an operation manual. On-site installation, calibration and training are not included for standard orders but can be arranged for laboratory setup. Remote guidance is provided.
Q10: What types of samples are compatible with this equipment?
A: The nano spectrophotometer measures nucleic acids (DNA, RNA, oligonucleotides) and proteins in aqueous solution within the concentration range and sample volume specification. Samples should be free of particulates that can scatter light, and properly dissolved in appropriate buffer. Very low concentration samples may be below the detection limit. Contaminants (phenol, guanidine, proteins) affect purity ratios and concentration accuracy. Users should apply the correct sample volume, ensure the sample forms a proper liquid column between pedestals, clean the pedestal thoroughly between samples, use appropriate blank (water or buffer), interpret purity ratios critically (A260/A280, A260/A230), and verify results with fluorometric methods for critical applications where accuracy is paramount. The pedestal surface should be inspected for scratches or damage that could affect measurement accuracy.
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