Cryostat Microtome LCRY-T2021

Introduction

Cryostat Microtome has a section thickness range that can be adjusted from 1 to 100 µm, and trimming thickness up to 600 µm. It combines an efficient freezing system with a semi-automatic microtome for consistent and accurate cryosectioning. This cryostat features a modular control system that supports both automatic and manual defrosting. The built-in waste tray and instrument rack enhance convenience and cleanliness. Our microtome is designed for slicing thin sections of biological tissues at low temperatures.

This microtome is designed to meet the rigorous requirements of modern laboratory operations, ensuring high precision, reliability, and ease of use for various experimental applications.

Applications

Our Cryostat Microtome is used for rapid cryosectioning of tissues in clinical pathology and intraoperative diagnostics. It enables precise preparation of frozen tissue samples for histological, immunohistochemical, and molecular analysis.

Specifications

Section Thickness Range	1 to 100 µm
Section Thickness Settings	1 μm to 20 μm, in 1 μm increments 20 μm to 50 μm, in 2 μm increments 50 μm to 100 μm, in 5 μm increments
Section Thickness Deviation	± 20%
Trimming Thickness Range	1 to 600 µm
Trimming Thickness Settings	1 μm to 50 μm, in 5 μm increments 50 μm to 100 μm, in 10 μm increments 100 μm to 600 μm, in 50 μm increments
Refrigeration Capacity	690 W
Refrigerant	R4490
Freezing Chamber Temperature Range	-35°C to -40°C
Chamber Capacity	20 specimen disc
Freezing chamber Defrost Method	Manual/ auto
Defrost Time	15 minutes
Quick-freezing Shelf Temp Range	-40°C to +40°C
Minimum Reaching Temperature	-60°C (±5°C)
Specimen Holder Freezing Points	18 (mechanical), 2 (semiconductor)
Specimen Horizontal Stroke	25 mm ± 1 mm
Specimen Vertical Stroke	59 mm ± 0.5 mm
Maximum Specimen Size	55 × 55 mm
Specimen Clamp Adjustable Angle	12° (X & Y axis), 360° (Z axis)
Slow Forward/Rewind Speed	300 µm/s
Fast Forward/Rewind Speed	900 µm/s
Operating Noise Level	Up to 70 dB(A)
Relative Humidity for Storage	Up to 60% (non-condensing)
Atmospheric Pressure Range	700 to 1060 hPa
Maximum Operating Altitude	Up to 2000 m
Power	1400 W at 220 to 240 V 1200 W at 110 to 127 V
Power Supply	AC 220 to 240 V 50 Hz AC 220 to 240 V 60 Hz AC 110 to 127 V 60 Hz
Dimension (W×D×H)	780 × 700 × 1280 mm
Packing Dimension	913 × 804 × 1467 mm
Net Weight	120 kg
Gross Weight	208 ± 10 kg

Features

UV sterilization and hibernation mode

Anti-fog heated observation window

Chromatic liquid crystal touch screen interface

Built-in waste tray and instrument rack

Blade ejector mechanism

Smooth handwheel with ergonomic design

FAQs

1. What is the Cryostat Microtome used for?

Cryostat Microtome is specifically designed for rapid and precise slicing of frozen biological tissue samples. It is primarily used in clinical pathology, intraoperative diagnostics, and histological research to prepare ultra-thin sections of tissues. These sections are then examined under microscopes for immunohistochemistry, molecular studies, or disease diagnostics, such as cancer evaluation. Its ability to maintain ultra-low temperatures ensures sample integrity and preserves tissue morphology.

2. What makes the Cryostat Microtome suitable for precise cryosectioning?

Cryostat Microtome integrates a semi-automatic microtome system with a high-efficiency refrigeration system, ensuring consistent sectioning at low temperatures. It offers adjustable section thickness from 1 to 100 µm, with trimming up to 600 µm. Fine controls allow users to set thickness increments based on their needs. Its blade ejector mechanism, smooth handwheel, and specimen clamp with multi-angle adjustments ensure ergonomic, accurate, and reproducible cutting, vital for histological and clinical precision.

3. How does the Cryostat Microtome maintain low temperatures during operation?

The Cryostat Microtome uses a powerful 690 W refrigeration system with dual compressors, R4490 refrigerant, and semiconductor (Peltier) cooling elements. These systems provide temperatures as low as -60°C (±5°C) at critical points like the specimen holder and freezing shelf. Additionally, mechanical and semiconductor-based freezing points enhance temperature uniformity across the chamber. This advanced cooling setup enables stable freezing of tissue, preventing ice crystal formation that can distort cellular structures.

4. What defrosting options are provided in the Cryostat Microtome ?

Cryostat Microtome offers both manual and automatic defrost modes, giving the user flexibility to clear frost build-up when necessary. The defrost cycle lasts about 15 minutes, and it helps in maintaining consistent cooling efficiency. Automated defrosting enhances convenience during extended usage while manual control gives precision when needed. This ensures that the observation window and internal chamber remain clear and effective during long procedures.

5. What safety and hygiene features are incorporated in this cryostat microtome?

Cryostat Microtome is equipped with UV sterilization to minimize the risk of contamination and maintain sterile working conditions. It also has a hibernation mode, which conserves power while keeping the system in a ready state. These features are especially important in medical and research labs handling sensitive or infectious samples. The enclosed design and noise level below 70 dB(A) also ensure a safe and quiet operating environment.