Introduction

Ultrasonic Homogenizer (Non-contact) is a cup-form homogenizer with 700 ml disruption capacity. With 19.5 to 20.5 KHz operation frequency, it is used for disruption of cells, for emulsification, homogenization of varied biological samples with minimum up to 5 μL volume. It can be used for breaking up chromosome and crushing cells aseptically across centrifugal glass tube.

This ultrasonic homogenizer is designed to meet the rigorous requirements of modern laboratory operations, ensuring high precision, reliability, and ease of use for various experimental applications.

Applications

Used in bimolecular fragmentation, cell disruption, ChIP assay (Chromatin immune precipitation), next generation sequencing , elute membrane proteins, homogeneous emulsification reactions and pre-treatment of ultrasonic exquisite samples.

Specifications

Operating frequency 19.5 to 20.5 KHz
Power consumption 1200 W
Horn 20 mm
Total working time 1 to 999 mins
Duty ratio 0.1 to 99.9 %
Disruption capacity 700 ml
Display Display
Temperature Display Yes ( prevent sample overheating )
Processing volume (0.1 to 2ml) × 4
Power supply 220 /110 V ± 0.5, 50 Hz / 60 Hz
Packing Dimension 560 × 440 × 480
Gross weight 19.4 kg

Features

Cup Tip style offers non-contact homogenization of micro scale samples

Excludes dregs circumstances of traditional probe

Samples are processed in sealed cup tubes eliminating aerosols and enhances biological safety (such as Mycobacterium)

Simultaneous processing of multiple vials of sterile or pathogenic samples

Programmed uninterrupted rotation of the centrifuge tube facilitates uniform distribution of ultrasonic energy

Imperative standard device for ChIP (chromatin immune precipitation) and shear research platforms

Higher efficacy, steadfast results and good repeatability

Standardized experimental method and advanced parameter settings

Optional coolant circulation system to maintain temperature at 4 °C in Eppendorf tube rotating base

FAQs

1. How does the It Ultrasonic Homogenizer (Non-contact) support non-contact processing of sensitive biological samples?

It Ultrasonic Homogenizer (Non-contact) uses a cup-tip design that allows ultrasonic energy to be transmitted through a sealed tube without direct probe contact. This non-contact method prevents cross-contamination and maintains sterility, which is especially important when working with hazardous or sensitive materials like Mycobacterium. It is ideal for aseptic processing of samples where direct contact could compromise sample integrity. This design is especially valuable in high-precision biological and clinical labs.

2. How does this Ultrasonic Homogenizer (Non-contact) ensure uniform energy distribution during sample processing?

The Ultrasonic Homogenizer (Non-contact) features a programmed uninterrupted rotation of the centrifuge tube during operation, which evenly distributes ultrasonic energy throughout the sample. This reduces hotspots and ensures homogeneous processing, improving reproducibility between sample batches. Uniform energy distribution is crucial in applications such as chromatin immunoprecipitation (ChIP) assays, where consistency in shearing is vital. The rotation mechanism enhances overall efficiency and output reliability.

3. How does the Ultrasonic Homogenizer (Non-contact) contribute to lab safety, especially when working with infectious agents?

Ultrasonic Homogenizer (Non-contact) allows the samples to be contained in sealed tubes within the sonication chamber, so there is no generation of aerosols or sample leakage. This makes it safe for processing pathogenic or volatile substances, reducing exposure risk for lab personnel. The system’s enclosed design eliminates contamination risks associated with traditional probe-based systems. This level of safety is essential in microbiology and infectious disease research labs.

4. Can this Ultrasonic Homogenizer (Non-contact) be used for temperature-sensitive samples?

Yes, our Ultrasonic Homogenizer (Non-contact) has a temperature display and monitoring function to prevent overheating during processing. For even better control, it offers an optional coolant circulation system that maintains the Eppendorf tube base at around 4°C. This feature is especially useful when working with enzymes, , or proteins that degrade at elevated temperatures. Maintaining low temperatures helps preserve sample quality and activity.

5. What maintenance practices help ensure long-term reliability of the Ultrasonic Homogenizer (Non-contact) ?

The Ultrasonic Homogenizer (Non-contact) requires the cup chamber to be cleaned regularly to remove any condensate or sample residues. User should check that tubes are sealed correctly before operation to avoid leaks that may damage the unit. Periodic inspection of the ultrasonic horn and connections helps detect early signs of wear. For labs using the coolant system, it is important to regularly replace or refill the coolant to ensure effective temperature regulation.

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