Introduction
An analytical HPLC (high-performance liquid chromatography) system is a high-resolution liquid chromatography instrument used to separate, identify, and quantify the components of a mixture, and it is one of the most widely used analytical instruments, used in the pharmaceutical, chemical, food, environmental, clinical, and research industries. The system consists of a solvent delivery system with high-pressure pumps that deliver the mobile phase at a controlled flow rate and composition, an injector for introducing the sample, a separation column packed with a stationary phase, a detector, such as a UV-Vis absorbance detector, fluorescence detector, refractive index detector, or mass spectrometer, and a data system; the sample components are separated as they travel through the column, based on their interactions with the stationary phase, and they are detected as they elute, producing a chromatogram, with the components identified by their retention times and quantified by their peak areas. Analytical HPLC systems are used for purity analysis of pharmaceutical products, for quantitative analysis of drug substances and formulations, for analyzing food additives, contaminants, and nutrients, for environmental analysis of pollutants, for clinical analysis of drugs and metabolites, for analyzing natural products, for quality control, for method development, and for many other applications, and they are available with various configurations, including isocratic and gradient systems, with features such as high sensitivity, high resolution, and automation. With their separation and quantification capability, analytical HPLC systems are essential for modern analytical chemistry.
Analytical HPLC System LAHS-T2010
Analytical System deliver a flow rate range of 0.0000 to 12.0000 mL/min ensuring precise solvent delivery for diverse analytical applications. The system offers a comprehensive detector...
Analytical HPLC System LAHS-T2010
Analytical System is equipped with advanced UV-Visible absorbance detector with wavelength range of 190nm to 700nm. Its double plunger reciprocating pump system ensures better flow stabi...
Analytical HPLC System LAHS-T2011
Analytical System offers a flow range of 0.001 to 10.000 mL/min (step size 0.001 mL/min). It features intelligent IP address allocation for automatic unit configuration. Its high-quality...
Analytical HPLC System LAHS-T2010
Analytical System is a binary pump-type system with a pump flow range of 0.001 to 10.000mL/min. It incorporates a mainstream split design for comprehensive system testing. Utilizes a new...
Analytical HPLC System LAHS-T2010
Analytical System features a Quaternary Pump with 0.001 to 10 ml/min pump flow rate. It incorporated a UV-Vis detector having a wavelength range of 190 to 800 nm. It is equipped with adv...
Analytical HPLC System LAHS-T2013
Analytical System features a Dual Binary High-Pressure Pump with 4 solvent channels. It has 2 detectors that can detect wavelengths from 190 to 800 nm. This detector features an automati...
Analytical HPLC System LAHS-T2012
Analytical System features a high-pressure constant flow pump with 2 solvent channels. It has a UV-visible detector that can detect wavelengths from 190 to 800 nm. This detector features...
Analytical HPLC System LAHS-T2011
Analytical System is a unit equipped with wavelength range of 190 nm to 700 nm and double plunger reciprocating pump system for constant flow pump. It has gradient kit system for test re...
Analytical HPLC System LAHS-T2010
Analytical System features a detector with a 190 nm to 800 nm wavelength range. Its low-pressure quaternary flow pump provides flexibility in solvent selection. The system is equipped wi...
Standards
IEC 61010-2-081:2015-Particular requirements for automatic and semi-automatic laboratory equipment for analysis and other purposes
Complies with the above standards, but is not limited to them.
Features
1. Analytical HPLC system for high-performance liquid chromatography separation.
2. Precision pumping, injection and detection for compound separation and quantification.
3. Suitable for pharmaceutical, chemical, environmental, food, clinical and research.
4. Includes pump, autosampler, column oven, detector, software and manual.
5. Supports qualitative and quantitative analysis of non-volatile and thermally labile compounds.
FAQ
Q1: What testing scenarios is this HPLC mainly applied to?
A: The analytical HPLC system is used in pharmaceutical analysis, chemical testing, environmental monitoring, food safety, clinical diagnostics, biotechnology and research to separate, identify and quantify non-volatile, thermally labile and polar compounds in liquid samples for quality control, regulatory compliance and research. It supports pharmaceutical potency and impurity testing, environmental contaminant analysis (pesticides, PAHs, pharmaceuticals in water), food safety testing (additives, contaminants, mycotoxins), clinical biomarker analysis, chemical manufacturing quality control, and research on compounds not suitable for GC. The HPLC provides high-resolution separation with versatile detection options, enabling detailed analysis of complex mixtures.
Q2: What standards does the HPLC comply with?
A: The analytical HPLC system complies with relevant IEC 61010 laboratory electrical safety standards, IEC 61326 for electromagnetic compatibility, applicable GB/T standards for analytical instruments, and relevant data integrity requirements (21 CFR Part 11, Annex 11) for regulated industries. Methods follow USP, EP, JP, AOAC, EPA, ISO and ASTM standards as applicable. Calibration should use certified reference standards traceable to international standards.
Q3: What is the warranty period for the whole machine and key components?
A: The whole HPLC system is covered by a 12-month warranty. The pump, autosampler, column oven, detector, electronics and software are covered, while columns, vials, seals, frits and fuses are consumables. Damage from improper use or unauthorized repair is excluded. Extended service contracts are standard for this analytical instrument.
Q4: Is this device difficult to operate? Is professional training required?
A: Operation requires trained analytical chemists familiar with HPLC, method development and data interpretation. We provide comprehensive training, operation manuals and application support. Proper column installation, method programming, calibration, sample preparation, system suitability testing, maintenance and data interpretation are important for accurate, reliable analysis.
Q5: What is the typical lead-time for order delivery?
A: Standard models require 7-30 working days. In-stock units can ship within 3-7 working days. Custom configurations or large built-to-order systems may require additional time, and we confirm the exact schedule before order confirmation.
Q6: Is regular calibration required? What is the recommended calibration cycle?
A: Calibration with certified reference standards per method or schedule. System suitability testing per run for regulated use. Pump flow and pressure verification periodically. Detector wavelength and performance calibration. Autosampler accuracy verified. Column performance and condition checked. Full system performance verification per schedule. Software updates and data integrity checks per regulatory requirements.
Q7: Are supporting consumables universal?
A: HPLC columns, vials, septa, frits, seals and solvents are available from multiple qualified suppliers, though column selection depends on the application. Long-term consumable cost depends on sample volume and column usage. Solvent waste requires proper handling and disposal.
Q8: Can I customize parameters or supporting accessories?
A: Customization includes detector type (UV-Vis, DAD, fluorescence, RI, ELSD, MS), pump type (binary, quaternary), autosampler capacity, column oven range, fraction collection, software features and accessories. Additional detectors, autosamplers and accessories can be ordered separately. Custom orders extend delivery lead-time.
Q9: Does the purchase include on-site installation and commissioning service?
A: Yes, analytical HPLC systems include on-site installation, commissioning, calibration, method setup and operator training by certified specialists. Site preparation guidance is provided before delivery to ensure power, solvent, waste and IT requirements are met.
Q10: What types of samples are compatible with this equipment?
A: The analytical HPLC system analyzes non-volatile, thermally labile, polar and ionic compounds in liquid samples (or extracts of solid samples) within the compound properties, concentration and column specification. Compounds should be soluble in the mobile phase and compatible with the column and detector. Very volatile compounds may be more suitable for GC. Different sample types require specific sample preparation (filtration, extraction, derivatization). Users should select appropriate column (stationary phase, particle size, dimensions) for the application, use proper sample preparation (0.22 or 0.45 micrometer filtration), degas mobile phases, calibrate with certified standards, perform system suitability testing per pharmacopoeial requirements, follow proper solvent handling and waste disposal, and for regulated use, follow data integrity requirements. The HPLC should be installed with proper solvent reservoir and waste handling. The column should be stored properly when not in use. The pump seals and frits should be replaced per manufacturer schedule. For pharmaceutical testing, follow validated methods and include appropriate quality controls. Waste solvents should be collected and disposed of per hazardous waste regulations.
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