Introduction
A fraction collector is a laboratory instrument used to collect the fractions of the liquid from the chromatographic and the other separation systems, in the individual containers, according to the time, the volume, or the signal, and it is used in the chemistry, the biochemistry, the pharmaceutical, and the research laboratories. The fraction collector consists of a collection rack or a carousel with the test tubes or the containers, a dispensing arm or a needle that delivers the liquid, a drive system that moves the arm to the containers, and a control and a timer or a signal interface, and it collects the fractions according to the programmed criteria, such as the fixed time intervals, the fixed volumes, or the triggers from the detector signal; the fraction collector is used for the collection of the fractions from the liquid chromatography, for the collection of the fractions from the preparative separations, for the purification of the compounds, for the collection of the fractions for the further analysis, and for many other applications, and it is available in various configurations, with the different numbers of the containers and the collection modes; the fraction collector is an essential instrument for the preparative chromatography. Fraction collectors are used in the chemistry and the biochemistry laboratories, in the pharmaceutical industry, in the research institutions, and for many other applications. With their fraction collection, fraction collectors are essential for the separation and the purification.
Fraction Collector LFRC-T2010
Fraction Collector 100 collection tubes, each with a 12 ml capacity. It features a durable -molded body and an ergonomically inclined 35° control panel. The collector is equipped with a...
Standards
Complies with the above standards, but is not limited to them.
Features
1. Fraction collector for automated collection of eluted fractions from chromatography columns.
2. Programmable tube/tray collection system for time-based, drop-based or peak-based fraction collection.
3. Suitable for chromatography, protein purification, HPLC, FPLC, chemical synthesis and research labs.
4. Includes collection tray, tube rack, dispensing arm, controller, tubing and operation manual.
5. Supports automated fraction collection for chromatographic purification and preparative separations.
FAQ
Q1: What testing scenarios is this collector mainly applied to?
A: The fraction collector is used in protein purification, chromatography laboratories, HPLC/FPLC systems, chemical synthesis, natural product isolation, pharmaceutical research, biotechnology, academic and industrial research to automatically collect eluted fractions from chromatography columns into test tubes or multi-well plates, enabling separation and purification of compounds based on elution time, drop count, or detector signal (peak detection). It supports protein purification (affinity, ion exchange, size exclusion chromatography), peptide and oligonucleotide synthesis, natural product isolation, preparative HPLC, and chemical compound purification.
Q2: What standards does the collector comply with?
A: The fraction collector follows relevant ISO, IEC and laboratory equipment standards including IEC 61010 (safety requirements for electrical laboratory equipment), and applicable good laboratory practice (GLP) and good manufacturing practice (GMP) guidelines for pharmaceutical and biotech applications. The hardware complies with applicable EMC standards (IEC 61326). For regulated environments, the system should be validated (IQ/OQ) and data should be traceable per 21 CFR Part 11 if applicable.
Q3: What is the warranty period for the whole collector and key components?
A: The whole fraction collector is covered by a 12-month warranty. The collection tray, tube rack, dispensing arm, drive mechanism, controller, display and housing are covered, while tubing, needles, collection tubes, seals, drive belts and fuses are consumables or accessories. Damage from improper use, buffer/solvent spillage (corrosion), mechanical jamming, or unauthorized repair is excluded. Extended warranty may be available.
Q4: Is this device difficult to operate? Is professional training required?
A: Operation requires trained laboratory personnel familiar with chromatography and fraction collection. We provide operation manuals and training. Proper system setup (tubing connections, needle placement, tube rack loading), collection mode selection (time-based, drop-based, peak-based with detector input), program setup (fraction duration/volume, tube change parameters, delay volume), operation monitoring (fraction collection progress, tube full detection), post-run handling (tube labeling, fraction storage), and maintenance (tubing replacement, needle cleaning, drive mechanism lubrication) are important for reliable fraction collection.
Q5: What is the typical lead-time for order delivery?
A: Standard models require 7-30 working days. In-stock units can ship within 3-7 working days. Custom configurations or large built-to-order systems may require additional time, and we confirm the exact schedule before order confirmation.
Q6: Is regular calibration required? What is the recommended calibration cycle?
A: Volume/dispensing accuracy verification recommended every 3-6 months (gravimetric verification of collected fraction volume). Time accuracy verification every 6-12 months. Drop counter calibration (if drop-based) every 3-6 months. Tube position/arm alignment check per schedule. Full collector performance verification annually. For regulated use, follow GMP/GLP calibration schedules.
Q7: Are supporting consumables universal?
A: Tubing (various sizes, materials - silicone, PEEK, PTFE), needles (dispensing tips, stainless steel or PEEK), collection tubes (1.5 mL, 15 mL, 50 mL centrifuge tubes, test tubes), multi-well plates (96-well, 384-well), tube racks, seals, O-rings, cleaning supplies and fuses are available from laboratory suppliers, though tube racks and some connectors may be system-specific. Long-term consumable cost includes tubing (periodic replacement - buffer/solvent causes degradation), needles (replace if clogged or damaged), and collection tubes (per run).
Q8: Can I customize parameters or supporting accessories?
A: Customization includes collection format (test tubes (various sizes), multi-well plates (96, 384), microcentrifuge tubes, bottles), number of fractions/tubes (typically 40-200+), collection modes (time, drop, peak, level sensor), dispensing arm configuration (single probe, multi-probe), cooling/heating option (for temperature-sensitive fractions - 4 degrees C cooling), integration (HPLC/FPLC system integration, detector input for peak detection, fraction collector software), data output (USB, Ethernet, LIMS connectivity), language and accessories. Additional tube racks, probes, tubing and accessories can be ordered separately.
Q9: Does the purchase include on-site installation and commissioning service?
A: Standard delivery includes the fraction collector, tubing, basic rack, power supply and instruction manual. On-site installation, integration with chromatography system, and training are not included for standard orders but can be arranged at additional cost. Remote guidance is provided.
Q10: What types of samples are compatible with this equipment?
A: The fraction collector collects fractions from various chromatography applications including protein and enzyme purification (affinity, ion exchange, size exclusion, hydrophobic interaction chromatography), nucleic acid purification (plasmid DNA, RNA, oligonucleotides), peptide and protein digest fractionation, natural product isolation (plant extracts, microbial cultures, marine organisms), pharmaceutical compound purification (API, intermediates, impurities), chemical synthesis product purification, preparative HPLC/FPLC fractions, and other chromatographic separations within the fraction volume, tube size, solvent compatibility and flow rate specification. Different sample types require specific collection parameters (fraction size based on peak width and flow rate, collection mode (time for well-separated peaks, peak for overlapping peaks with detector triggering), delay volume calibration (to account for tubing volume between detector and fraction collector - critical for accurate peak collection), and fraction storage conditions (4 degrees C for proteins/enzymes, room temperature for stable small molecules,
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