Introduction
A multi concentration inhalation exposure system is an instrument used for the exposure of the animals to the airborne substances at the multiple concentrations, for the inhalation toxicology and the research, and it is used in the toxicology, the pharmaceutical, the environmental, and the research institutions. The multi concentration inhalation exposure system generates the test atmospheres with the airborne substances, such as the gases, the vapors, and the aerosols, at the multiple concentrations, and it exposes the animals in the exposure chambers to the atmospheres, with the control and the monitoring of the concentrations, the airflow, and the environmental conditions; the multi concentration inhalation exposure system consists of the atmosphere generation system, the exposure chambers, the concentration control and the monitoring system, the airflow system, and the data system, and it provides features such as the programmable exposure and the data logging; the multi concentration inhalation exposure system is used for the inhalation toxicity studies, for the evaluation of the effects of the airborne substances, for the pharmaceutical research, for the environmental health research, and for many other applications, and it is an essential equipment for the inhalation research. Multi concentration inhalation exposure systems are used in the toxicology laboratories, in the pharmaceutical research, in the environmental research, in the research institutions, and for many other applications. With their multi concentration exposure, multi concentration inhalation exposure systems are essential for the inhalation studies.
Multi-Concentration Nose-Only Inhalation Exposure System T-MIS-S2100
Standards
Directive 2010/63/EU-Protection of animals used for scientific purposes
OECD Test Guidelines-genetic toxicology (bacterial reverse mutation / Ames) and inhalation toxicity studies
Complies with the above standards, but is not limited to them.
Features
1. Multi-concentration inhalation exposure system for toxicology and pharmacology research.
2. Generates and controls multiple aerosol or gas concentrations for simultaneous exposure groups.
3. Suitable for pharmaceutical, chemical, environmental and regulatory inhalation studies.
4. Includes exposure chambers, aerosol generator, monitoring and control system.
5. Supports nose-only, whole-body or head-only exposure configurations.
FAQ
Q1: What testing scenarios is this system mainly applied to?
A: The multi-concentration inhalation exposure system is used in pharmaceutical toxicology, chemical safety assessment, environmental health research, regulatory testing laboratories and academic institutions to conduct controlled inhalation exposure studies with multiple concentration levels simultaneously. It supports acute and repeated dose inhalation toxicity testing, pharmacokinetic inhalation studies, aerosol drug delivery research, air pollution health effect studies and regulatory compliance testing for chemicals, pesticides and pharmaceuticals. The multi-concentration capability allows simultaneous exposure of multiple animal groups to different dose levels, improving study efficiency and reducing inter-experiment variability. It is essential for facilities conducting GLP-compliant inhalation toxicology studies required for drug development, chemical registration and environmental risk assessment where precise control of exposure concentration, particle size and duration is critical for regulatory acceptance.
Q2: What standards does the system comply with?
A: The system supports studies conducted under OECD Test Guidelines for inhalation toxicity (TG 403, 412, 413), EPA and FDA guidelines, and GLP good laboratory practice regulations. Equipment performance may reference ISO standards for aerosol generation and measurement. Animal welfare follows applicable animal care and use regulations including AAALAC and local ethics committee requirements.
Q3: What is the warranty period for the whole machine and key components?
A: The whole system is covered by a 12-month warranty. The aerosol generator, exposure chambers, monitoring sensors and control system are covered, while filters, tubing and seals are consumables excluded from warranty. Damage from improper test article use or unauthorized modification is excluded. Extended service contracts are available for this specialized system.
Q4: Is this device difficult to operate? Is professional training required?
A: Operation requires specialist training in inhalation toxicology, aerosol science and animal handling. We provide comprehensive training, operation manuals and application support. Proper system setup, concentration calibration, particle size measurement and animal welfare procedures are essential for valid study results.
Q5: What is the typical lead-time for order delivery?
A: Standard models require 7-30 working days. In-stock units can ship within 3-7 working days. Custom configurations or large built-to-order systems may require additional time, and we confirm the exact schedule before order confirmation.
Q6: Is regular calibration required? What is the recommended calibration cycle?
A: Concentration monitoring sensors should be calibrated before each study and annually by certified methods. Aerosol generator output and particle size distribution should be verified periodically. Flow measurement calibration follows the manufacturer schedule. Full system validation is recommended for GLP studies and after major maintenance.
Q7: Are supporting consumables universal?
A: Filters, tubing, seals and animal holders are available from the manufacturer or authorized distributors. Test articles and calibration gases are sourced separately. Long-term consumable and service cost is significant for this specialized system.
Q8: Can I customize parameters or supporting accessories?
A: Customization includes exposure type (nose-only, whole-body, head-only), number of concentration levels, chamber size, aerosol generator type and monitoring configuration. Custom orders require detailed technical specification and extend lead-time. Users should define study requirements, animal species and test article properties before design.
Q9: Does the purchase include on-site installation and commissioning service?
A: Yes, inhalation exposure systems include on-site installation, commissioning, validation and operator training by certified engineers and application specialists. Site preparation guidance is provided before delivery to ensure ventilation, power, exhaust and animal facility requirements are met.
Q10: What types of samples and applications are compatible with this equipment?
A: The system handles aerosols, dusts, gases and vapors within the generator and concentration range. Highly toxic, flammable or reactive test articles require special safety containment and engineering controls. Users should verify test article compatibility with system materials, ensure proper exhaust treatment, and follow GLP procedures, animal welfare regulations and institutional ethics requirements for all inhalation studies. Concentration uniformity and particle size should be characterized and documented for each study.
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